Christopher Nolan's blockbuster biopic “Oppenheimer” dominated the 81st Golden Globes, winning five awards including best drama, while Yorgos Lanthimos' Frankenstein riff “Poor Things” pulled off an upset victor over “Barbie” to triumph in the best comedy or musical category.

If awards season has been building toward a second match-up of Barbenheimer, this round went to “Oppenheimer." The film also won best director for Nolan, best drama actor for Cillian Murphy, best supporting actor for Robert Downey Jr. and for Ludwig Göransson’s score.

“I don't think it was a no-brainer by any stretch of the imagination to make a three-hour talky movie — R-rated by the way — about one of the darkest developments in our history," said producer Emma Thomas accepting the night’s final award and thanking Universal chief Donna Langley.

Along with best comedy or musical, “Poor Things” also won for Emma Stone's performance as Bella, a Victorian-era woman experiencing a surreal sexual awakening.

“I see this as a rom-com,” said Stone. “But in the sense that Bella falls in love with life itself, rather than a person. She accepts the good and the bad in equal measure, and that really made me look at life differently.”

Lily Gladstone won best actress in a dramatic film for Martin Scorsese's “Killers of the Flower Moon.” Gladstone, who began her speech speaking the language of her native tribe, Blackfeet Nation, is the first Indigenous winner in the category.

“This is a historic win,” said Gladstone. “It doesn’t just belong to me.”

The Globes were in their ninth decade but facing a new and uncertain chapter. After a tumultuous few years of scandal, the Hollywood Foreign Press Association was dissolved, leaving a new Globes, on a new network (CBS), to try to regain its perch as the third biggest award show of the year, after the Oscars and Grammys. Even the menu (sushi from Nobu) was remade.

“Golden Globes journalists, thank you for changing your game, therefore changing your name,” said Downey in his acceptance speech.

It got off to a rocky start. Host Jo Koy took the stage at the Beverly Hilton International Ballroom in Beverly Hills, California . The Filipino American stand-up hit on some expected topics: Ozempic, Meryl Streep’s knack for winning awards and the long-running “Oppenheimer.” (“I needed another hour.”)

After one joke flubbed, Koy, who was named host after some bigger names reportedly passed, also noted how fast he was thrust into the job.

“Yo, I got the gig 10 days ago. You want a perfect monologue?” said Koy. “I wrote some of these and they’re the ones you’re laughing at.”

Downey’s win, his third Globe, denied one to “Kenergy.” Ryan Gosling had been seen as his stiffest competition, just one of the many head-to-head contests between “Oppenheimer” and Greta Gerwig’s “Barbie.” The filmmakers faced each other in the best director category, where Nolan triumphed.

It was two hours before “Barbie,” the year's biggest hit with more than $1.4 billion in ticket sales, won an award Sunday. Billie Eilish's “What Was I Made For?” took best song, and swiftly after, “Barbie” took the Globes' new honor for “cinematic and box office achievement.” Some thought that award might go to Taylor Swift, whose “Taylor Swift: The Eras Tour” also set box-office records. Swift, though, remains winless in five Globe nods.

Margot Robbie, star and producer of “Barbie,” accepted the award in a pink gown modeled after 1977's Superstar Barbie.

“We’d like to dedicate this to every single person on the planet who dressed up and went to the greatest place on Earth: the movie theaters,” said Robbie.

“Barbie” and “Oppenheimer,” two blockbusters brought together by a common release date, also faced off in the best screenplay category. But in an upset, Justine Triet and Arthur Harari won for the script to the French courtroom drama “Anatomy of a Fall.” Later, Triet’s film picked up best international film, too.

Though the Globes have no direct correlation with the Academy Awards, they can boost campaigns at a crucial juncture. Oscar nomination voting starts Thursday, and the twin sensations of Barbenheimer remain frontrunners.

Other contenders loom, though, like “Poor Things” and “The Holdovers.”

Paul Giamatti and Da'Vine Joy Randolph both won for Alexander Payne’s “The Holdovers.” Giamatti, reuniting with Payne two decades after “Sideways,” won best actor and Randolph won for her supporting performance as a grieving woman in the 1970s-set boarding school drama.

“Oh, Mary you have changed my life,” Randolph said of her character. “You have made me feel seen in so many ways that I have never imagined.”

Hayao Miyazaki's “The Boy and the Heron” won best animated film, an upset over “Spider-Man: Across the Spider-Verse.”

The final season of “Succession” cleaned up on the television side. It won best drama series for the third time, a mark that ties a record set by “Mad Men” and “The X-Files." Three stars from the HBO series also won: Matt Macfadyen, Sarah Snook and Kieran Culkin.

“It is bittersweet, but things like this make it rather sweeter,” said “Succession” creator Jesse Armstrong.

Hulu's “The Bear” also came away with a trio of awards, including best comedy series. Jeremy Allen White won for the second time, but this time he had company. Ayo Edebiri won her first Globe for her leading performance in the Hulu show's second season. She thanked the assistants of her agents and managers.

“To the people who answer my emails, you’re the real ones,” said Edebiri.

“Beef” won three awards: best limited series as well as acting awards for Ali Wong and Steven Yeun.

The Globes also added a new stand-up special award. That went, surprisingly, to Ricky Gervais, who didn’t attend the show he so often hosted. Some expected Chris Rock to win for “Selective Outrage,” his stand-up response to the Will Smith slap.

A few years ago, the Golden Globes were on the cusp of collapse. After The Los Angeles Times reported that the HFPA had no Black members, Hollywood boycotted the organization. The 2022 Globes were all but canceled and taken off TV. After reforms, the Globes returned to NBC last year in a one-year deal, but the show was booted to Tuesday evening. With Jerrod Carmichael hosting, the telecast attracted 6.3 million viewers, a new low on NBC and a far cry from the 20 million that once tuned in.

The Golden Globes were acquired by Eldridge Industries and Dick Clark Productions, which Penske Media owns, and turned into a for-profit venture. The HFPA (which typically numbered around 90 voters) was dissolved and a group of some 300 entertainment journalists from around the world now vote for the awards.

Questions still remain about the Globes’ long-term future, but their value to Hollywood studios remains providing a marketing boost to awards contenders. (The Oscars won’t be held until March 10.) This year, because of the actors and writers strikes, the Globes are airing ahead of the Emmys, which were postponed to Jan. 15.

With movie ticket sales still 20% off the pre-pandemic pace and the industry facing a potentially perilous 2024 at the box office, Hollywood needed the Golden Globes as much as it ever has.

The most comical evaluation on the Globes came from presenters Will Ferrell and Kristin Wiig, who blamed the awards body for the constant interruption of a song they found irresistible while otherwise solemnly presenting best actor in a drama.

A furious, dancing Ferrell shouted: “The Golden Globes have not changed!”